Given the significant role of penicillin‐nonsusceptible Streptococcus pneumoniae in inducing severe infectious diseases, identifying serotypes and genotypes that can mediate antimicrobial resistance has become a pillar of treatment strategies. This… Click to show full abstract
Given the significant role of penicillin‐nonsusceptible Streptococcus pneumoniae in inducing severe infectious diseases, identifying serotypes and genotypes that can mediate antimicrobial resistance has become a pillar of treatment strategies. This study aims to determine the correlation between the minimum inhibitory concentration of antimicrobial agents and amino acid mutations in penicillin‐binding proteins. Moreover, molecular serotyping and multiple‐locus variable number tandem repeat analysis typing were first‐ever performed to characterize the invasive penicillin‐nonsusceptible S. pneumoniae isolates in Iran.
Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2022
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