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Is pre‐heat necessary for the measurement of 8‐oxo‐7,8‐dihydroguanosine and 8‐oxo‐7,8‐dihydro‐2′‐deoxyguanosine in urine samples

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It is currently unclear for the necessary of pre‐heating urine samples for the accurate determination of 8‐oxo‐7,8‐dihydroguanosine (8‐oxoG) and 8‐oxo‐7,8‐dihydro‐2′‐deoxyguanosine (8‐oxodG). Thus, we conducted this study to evaluate the effect… Click to show full abstract

It is currently unclear for the necessary of pre‐heating urine samples for the accurate determination of 8‐oxo‐7,8‐dihydroguanosine (8‐oxoG) and 8‐oxo‐7,8‐dihydro‐2′‐deoxyguanosine (8‐oxodG). Thus, we conducted this study to evaluate the effect of pre‐heat (i.e., to 37°C) on the accurate measurement of 8‐oxoG and 8‐oxodG in frozen urine samples.

Keywords: oxo; oxo dihydro; oxo dihydroguanosine; pre heat; dihydro deoxyguanosine; urine samples

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2022

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