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Does walking during chemotherapy impact p16INK4a levels in women with early breast cancer

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Increased p16INK4a (p16) expression is directly related to cellular senescence and is a robust biomarker of aging in humans. Prior studies have shown that levels of p16 dramatically increase in… Click to show full abstract

Increased p16INK4a (p16) expression is directly related to cellular senescence and is a robust biomarker of aging in humans. Prior studies have shown that levels of p16 dramatically increase in breast cancer patients who have received adjuvant chemotherapy. This study investigated whether moderate physical activity during chemotherapy would attenuate the expected rise in p16 expression.

Keywords: p16ink4a; walking chemotherapy; impact p16ink4a; chemotherapy impact; breast cancer

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2022

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