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Giant plasma cells with multiple immature nuclei in a young woman with newly diagnosed multiple myeloma

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Multiple myeloma with giant multinucleated plasma cells is a very rare entity and mostly reported cases are dated. This plasma cell morphology has been observed after monoclonal antibody treatments, such… Click to show full abstract

Multiple myeloma with giant multinucleated plasma cells is a very rare entity and mostly reported cases are dated. This plasma cell morphology has been observed after monoclonal antibody treatments, such as daratumumab, and patients have experienced a worse prognosis with partial responses and a high rate of relapse.

Keywords: myeloma giant; multiple myeloma; plasma cells

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2022

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