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Significantly elevated serum human epididymis protein‐4 in chronic kidney disease patients without ovarian cancer: A large‐scale retrospective study

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Human epididymis protein‐4 (HE‐4) is a commonly used biomarker for diagnosing ovarian cancer. Elevated HE‐4 has also been observed in various benign conditions including chronic kidney disease (CKD); however, generalizability… Click to show full abstract

Human epididymis protein‐4 (HE‐4) is a commonly used biomarker for diagnosing ovarian cancer. Elevated HE‐4 has also been observed in various benign conditions including chronic kidney disease (CKD); however, generalizability and statistical power of previous studies have been limited by small sample sizes.

Keywords: epididymis protein; ovarian cancer; chronic kidney; human epididymis; kidney disease

Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2023

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