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Mutations in KRAS, NRAS, BRAF, and PIK3CA genes are critical factors in clinical evaluation of colorectal cancer (CRC) development and progression. In Iran, however, the data regarding genetic profile of… Click to show full abstract
Mutations in KRAS, NRAS, BRAF, and PIK3CA genes are critical factors in clinical evaluation of colorectal cancer (CRC) development and progression. In Iran, however, the data regarding genetic profile of CRC patients is limited except for KRAS exon2 and BRAF V600F mutations. This study aimed to investigate the mutational spectrum and prognostic effects of these genes and explore the relationship between these mutations and clinicopathological features of CRC.
Keywords:
braf pik3ca;
kras nras;
pik3ca mutation;
colorectal cancer;
nras braf
Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2023
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Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2023
Link to full text (if available)
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recommendations!