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Non‐invasive prenatal testing (NIPT) using cell‐free DNA (cfDNA) circulating in maternal blood provides a sensitive and specific screening technique for common fetal aneuploidies, but the high cost and workflow complexity… Click to show full abstract
Non‐invasive prenatal testing (NIPT) using cell‐free DNA (cfDNA) circulating in maternal blood provides a sensitive and specific screening technique for common fetal aneuploidies, but the high cost and workflow complexity of conventional methodologies limit its widespread implementation. A unique rolling circle amplification methodology reduces cost and complexity, providing a promising alternative for increased global accessibility as a first‐tier test.
Keywords:
prenatal testing;
rolling circle;
non invasive;
circle amplification;
invasive prenatal
Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2023
Link to full text (if available)
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Journal Title: Journal of Clinical Laboratory Analysis
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!