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The habenula as a novel link between the homeostatic and hedonic pathways in cancer‐associated weight loss: a pilot study

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Little is known about the brain mechanisms underlying cancer‐associated weight loss (C‐WL) in humans despite this condition negatively affecting their quality of life and survival. We tested the hypothesis that… Click to show full abstract

Little is known about the brain mechanisms underlying cancer‐associated weight loss (C‐WL) in humans despite this condition negatively affecting their quality of life and survival. We tested the hypothesis that patients with C‐WL have abnormal connectivity in homeostatic and hedonic brain pathways together with altered brain activity during food reward.

Keywords: cancer associated; homeostatic hedonic; weight loss; associated weight

Journal Title: Journal of Cachexia, Sarcopenia and Muscle
Year Published: 2018

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