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Serum creatinine and cystatin C‐based diagnostic indices for sarcopenia in advanced non‐small cell lung cancer

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Sarcopenia is an important prognostic factor of lung cancer. The serum creatinine/cystatin C ratio (CCR) and the sarcopenia index (SI, serum creatinine × cystatin C‐based glomerular filtration rate) are novel… Click to show full abstract

Sarcopenia is an important prognostic factor of lung cancer. The serum creatinine/cystatin C ratio (CCR) and the sarcopenia index (SI, serum creatinine × cystatin C‐based glomerular filtration rate) are novel screening tools for sarcopenia; however, the diagnostic accuracy of the CCR and SI for detecting sarcopenia remains unknown. We aimed to explore and validate the diagnostic values of the CCR and SI for determining sarcopenia in non‐small cell lung cancer (NSCLC) and to explore their prognostic values for overall survival.

Keywords: sarcopenia; lung cancer; creatinine cystatin; serum creatinine

Journal Title: Journal of Cachexia, Sarcopenia and Muscle
Year Published: 2022

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