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Cachexia‐anorexia syndrome is a complex metabolic condition characterized by skeletal muscle wasting, reduced food intake and prominent involvement of systemic and central inflammation. Here, the gut barrier function was investigated… Click to show full abstract
Cachexia‐anorexia syndrome is a complex metabolic condition characterized by skeletal muscle wasting, reduced food intake and prominent involvement of systemic and central inflammation. Here, the gut barrier function was investigated in pancreatic cancer‐induced cachexia mouse models by relating intestinal permeability to the degree of cachexia. We further investigated the involvement of the gut–brain axis and the crosstalk between tumour, gut and hypothalamus in vitro.
Keywords:
lipopolysaccharide induced;
inflammation;
induced hypothalamic;
cachexia anorexia;
cachexia;
cancer
Journal Title: Journal of Cachexia, Sarcopenia and Muscle
Year Published: 2022
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Journal Title: Journal of Cachexia, Sarcopenia and Muscle
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!