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Grip strength is inversely associated with DNA methylation age acceleration

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There is a large body of evidence linking muscular weakness, as determined by low grip strength, to a host of negative ageing‐related health outcomes. Given these links, grip strength has… Click to show full abstract

There is a large body of evidence linking muscular weakness, as determined by low grip strength, to a host of negative ageing‐related health outcomes. Given these links, grip strength has been labelled a ‘biomarker of aging’; and yet, the pathways connecting grip strength to negative health consequences are unclear. The objective of this study was to determine whether grip strength was associated with measures of DNA methylation (DNAm) age acceleration.

Keywords: strength; dna methylation; age acceleration; grip strength

Journal Title: Journal of Cachexia, Sarcopenia and Muscle
Year Published: 2022

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