Photo from wikipedia
Following muscle injury, fibro‐adipogenic progenitors (FAPs) are rapidly activated and undergo apoptosis at the resolution stage, which is required for proper muscle regeneration. When excessive FAPs remain, it contributes to… Click to show full abstract
Following muscle injury, fibro‐adipogenic progenitors (FAPs) are rapidly activated and undergo apoptosis at the resolution stage, which is required for proper muscle regeneration. When excessive FAPs remain, it contributes to fibrotic and fatty infiltration, impairing muscle recovery. Mechanisms controlling FAP apoptosis remain poorly defined. We hypothesized that AMP‐activated protein kinase (AMPK) in FAPs mediates their apoptosis during the muscle regeneration.
Keywords:
amp activated;
fibro adipogenic;
muscle;
muscle regeneration;
adipogenic progenitors
Journal Title: Journal of Cachexia, Sarcopenia and Muscle
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Journal of Cachexia, Sarcopenia and Muscle
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!