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Chemical reprogramming of melanocytes to skeletal muscle cells

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Direct cell‐fate conversion by chemical reprogramming is promising for regenerative cell therapies. However, this process requires the reactivation of a set of master transcription factors (TFs) of the target cell… Click to show full abstract

Direct cell‐fate conversion by chemical reprogramming is promising for regenerative cell therapies. However, this process requires the reactivation of a set of master transcription factors (TFs) of the target cell type, which has proven challenging using only small molecules.

Keywords: melanocytes skeletal; chemical reprogramming; muscle cells; muscle; reprogramming melanocytes; skeletal muscle

Journal Title: Journal of Cachexia, Sarcopenia and Muscle
Year Published: 2023

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