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Sarcopenia, the age‐associated decline in skeletal muscle mass and strength, has long been considered a disease of muscle only, but accumulating evidence suggests that sarcopenia could originate from the neural… Click to show full abstract
Sarcopenia, the age‐associated decline in skeletal muscle mass and strength, has long been considered a disease of muscle only, but accumulating evidence suggests that sarcopenia could originate from the neural components controlling muscles. To identify early molecular changes in nerves that may drive sarcopenia initiation, we performed a longitudinal transcriptomic analysis of the sciatic nerve, which governs lower limb muscles, in aging mice.
Keywords:
sciatic nerve;
longitudinal transcriptomic;
muscle;
pathology;
sarcopenia;
transcriptomic analysis
Journal Title: Journal of Cachexia, Sarcopenia and Muscle
Year Published: 2023
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Journal Title: Journal of Cachexia, Sarcopenia and Muscle
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!