The aryl hydrocarbon receptor (AHR) is expressed in the intestine and liver, where it has pleiotropic functions and target genes. This study aims to explore the potential implication of AHR… Click to show full abstract
The aryl hydrocarbon receptor (AHR) is expressed in the intestine and liver, where it has pleiotropic functions and target genes. This study aims to explore the potential implication of AHR in cancer cachexia, an inflammatory and metabolic syndrome contributing to cancer death. Specifically, we tested the hypothesis that targeting AHR can alleviate cachectic features, particularly through the gut–liver axis.
Keywords:
hydrocarbon receptor;
aryl hydrocarbon;
cancer cachexia;
cancer
Journal Title: Journal of Cachexia, Sarcopenia and Muscle
Year Published: 2023
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Journal Title: Journal of Cachexia, Sarcopenia and Muscle
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!