With a decline of 17β‐estradiol (E2) at menopause, E2 has been implicated in the accompanied loss of skeletal muscle mass and strength. We aimed at characterizing transcriptomic responses of skeletal… Click to show full abstract
With a decline of 17β‐estradiol (E2) at menopause, E2 has been implicated in the accompanied loss of skeletal muscle mass and strength. We aimed at characterizing transcriptomic responses of skeletal muscle to E2 in female mice, testing the hypothesis that genes and pathways related to contraction and maintenance of mass are differentially expressed in ovariectomized mice with and without E2 treatment.
Keywords:
skeletal muscle;
treatment;
ovariectomized mice;
muscle;
transcriptomic profiling;
profiling reveals
Journal Title: Journal of Cachexia, Sarcopenia and Muscle
Year Published: 2025
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Journal Title: Journal of Cachexia, Sarcopenia and Muscle
Year Published: 2025
Link to full text (if available)
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recommendations!