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Synthesis and Antimicrobial Activity of Azolyl Pyrimidines

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A new class of azolyl pyrimidines linked by diamino sulfone moiety was prepared and studied their antimicrobial activity. Chloro-substituted and nitro-substituted thiazolyl pyrimidines (9c and 9e) showed excellent antibacterial activity… Click to show full abstract

A new class of azolyl pyrimidines linked by diamino sulfone moiety was prepared and studied their antimicrobial activity. Chloro-substituted and nitro-substituted thiazolyl pyrimidines (9c and 9e) showed excellent antibacterial activity against Bacillus subtilis, while imidazolyl pyrimidines (10c and 10e) exhibited promising antifungal activity against Aspergillus niger.

Keywords: antimicrobial activity; azolyl pyrimidines; synthesis antimicrobial; activity azolyl; activity

Journal Title: Journal of Heterocyclic Chemistry
Year Published: 2017

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