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A green and highly efficient protocol for one-pot, step-wise, alternative syntheses of quinoline-substituted bi(indolyl)methanes has been described by the condensation of N-methyl or N-ethyl quinolone-4-one-3-carbaldehydes 1a and b with indole… Click to show full abstract
A green and highly efficient protocol for one-pot, step-wise, alternative syntheses of quinoline-substituted bi(indolyl)methanes has been described by the condensation of N-methyl or N-ethyl quinolone-4-one-3-carbaldehydes 1a and b with indole 2a–f in water containing a catalytic amount of l-proline to afford the title compounds 5a–l in high yields and in shorter reaction times. This reaction involves easy workup without using column chromatography.
Keywords:
one pot;
pot step;
step wise;
syntheses quinoline;
wise alternative;
alternative syntheses
Journal Title: Journal of Heterocyclic Chemistry
Year Published: 2017
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Journal Title: Journal of Heterocyclic Chemistry
Year Published: 2017
Link to full text (if available)
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recommendations!