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An environmentally benign procedure for the synthesis of 2-(3-alkyl-4-oxo-2-thioxo-1,3-thiazinan-5-yl)acetic acid via the one-pot three-component reaction of primary amines, carbon disulfide, and itaconic anhydride in water is described. Also, this protocol… Click to show full abstract
An environmentally benign procedure for the synthesis of 2-(3-alkyl-4-oxo-2-thioxo-1,3-thiazinan-5-yl)acetic acid via the one-pot three-component reaction of primary amines, carbon disulfide, and itaconic anhydride in water is described. Also, this protocol was expanded for the synthesis of succinic acids containing a dithiocarbamate group by using hindered primary amines and secondary amines.
Keywords:
reaction situ;
itaconic anhydride;
anhydride water;
investigation reaction
Journal Title: Journal of Heterocyclic Chemistry
Year Published: 2017
Link to full text (if available)
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Journal Title: Journal of Heterocyclic Chemistry
Year Published: 2017
Link to full text (if available)
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recommendations!