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A variety of 3,4-disubstituted pyrroles and pyrazoles were synthesized by the treatment of 1,3-dipolar reagents viz., tosylmethyl isocyanide, and diazomethane to heteroaryl chalcones and evaluated for their antimicrobial activity. Among… Click to show full abstract
A variety of 3,4-disubstituted pyrroles and pyrazoles were synthesized by the treatment of 1,3-dipolar reagents viz., tosylmethyl isocyanide, and diazomethane to heteroaryl chalcones and evaluated for their antimicrobial activity. Among all the tested compounds, 14b and 15b displayed promising antimicrobial activity when compared with the standards particularly against Bacillus subtilis and Aspergillus niger.
Keywords:
activity new;
disubstituted pyrroles;
antimicrobial activity;
synthesis antimicrobial;
activity;
pyrroles pyrazoles
Journal Title: Journal of Heterocyclic Chemistry
Year Published: 2018
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Journal Title: Journal of Heterocyclic Chemistry
Year Published: 2018
Link to full text (if available)
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recommendations!