Imidazo[1,2‐a]indoles, 2,3‐dihydro‐1H‐imidazo[1,2‐a]‐indoles and benzo[4,5]imidazo[1,2‐a]indoles are rare yet valuable classes of nitrogen‐containing heterocycles, offering diverse applications in pharmaceutical development and advanced materials research. Despite their potential medicinal applications, efficient synthesis methods… Click to show full abstract
Imidazo[1,2‐a]indoles, 2,3‐dihydro‐1H‐imidazo[1,2‐a]‐indoles and benzo[4,5]imidazo[1,2‐a]indoles are rare yet valuable classes of nitrogen‐containing heterocycles, offering diverse applications in pharmaceutical development and advanced materials research. Despite their potential medicinal applications, efficient synthesis methods for these substances remain limited. This review provides an in‐depth analysis of emerging synthetic approaches for imidazo[1,2‐a]indoles and benzo[4,5]imidazo[1,2‐a]indoles, including metal‐catalyzed and metal‐free methods, as well as metal‐catalyzed synthesis of 2,3‐dihydro‐1H‐imidazo[1,2‐a]indoles, offering valuable insights into effective synthetic strategies.
Journal Title: Journal of Heterocyclic Chemistry
Year Published: 2025
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