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Early structural brain development in infants exposed to HIV and antiretroviral therapy in utero in a South African birth cohort

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There is a growing population of children who are HIV‐exposed and uninfected (HEU) with the successful expansion of antiretroviral therapy (ART) use in pregnancy. Children who are HEU are at… Click to show full abstract

There is a growing population of children who are HIV‐exposed and uninfected (HEU) with the successful expansion of antiretroviral therapy (ART) use in pregnancy. Children who are HEU are at risk of delayed neurodevelopment; however, there is limited research on early brain growth and maturation. We aimed to investigate the effects of in utero exposure to HIV/ART on brain structure of infants who are HEU compared to HIV‐unexposed (HU).

Keywords: early structural; antiretroviral therapy; brain development; brain; structural brain

Journal Title: Journal of the International AIDS Society
Year Published: 2022

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