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Feasibility of using half‐dose Gd‐BOPTA for delayed gadolinium‐enhanced MRI of cartilage (dGEMRIC) at the knee, compared with standard‐dose Gd‐DTPA

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We sought to replace full‐dose Gd‐DTPA with safer and lower‐dose contrast agents for delayed gadolinium‐enhanced MRI of cartilage (dGEMRIC). Gd‐BOPTA has a lower intrinsic nephrogenic systemic fibrosis risk and a… Click to show full abstract

We sought to replace full‐dose Gd‐DTPA with safer and lower‐dose contrast agents for delayed gadolinium‐enhanced MRI of cartilage (dGEMRIC). Gd‐BOPTA has a lower intrinsic nephrogenic systemic fibrosis risk and a 2‐fold higher relaxivity at 3T; thus, the contrast agent dose may be halved, further reducing contrast agent‐dependent risks.

Keywords: mri cartilage; gadolinium enhanced; delayed gadolinium; dose dtpa; enhanced mri; dose

Journal Title: Journal of Magnetic Resonance Imaging
Year Published: 2019

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