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Unraveling the MRI‐Based Microstructural Signatures Behind Primary Progressive and Relapsing–Remitting Multiple Sclerosis Phenotypes

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The mechanisms driving primary progressive and relapsing–remitting multiple sclerosis (PPMS/RRMS) phenotypes are unknown. Magnetic resonance imaging (MRI) studies support the involvement of gray matter (GM) in the degeneration, highlighting its… Click to show full abstract

The mechanisms driving primary progressive and relapsing–remitting multiple sclerosis (PPMS/RRMS) phenotypes are unknown. Magnetic resonance imaging (MRI) studies support the involvement of gray matter (GM) in the degeneration, highlighting its damage as an early feature of both phenotypes. However, the role of GM microstructure is unclear, calling for new methods for its decryption.

Keywords: progressive relapsing; primary progressive; relapsing remitting; remitting multiple; multiple sclerosis

Journal Title: Journal of Magnetic Resonance Imaging
Year Published: 2021

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