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Hepatic Iron Quantification Using a Free‐Breathing 3D Radial Gradient Echo Technique and Validation With a 2D Biopsy‐Calibrated R2* Relaxometry Method

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Hepatic iron content (HIC) is an important parameter for the management of iron overload. Non‐invasive HIC assessment is often performed using biopsy‐calibrated two‐dimensional breath‐hold Cartesian gradient echo (2D BH GRE)… Click to show full abstract

Hepatic iron content (HIC) is an important parameter for the management of iron overload. Non‐invasive HIC assessment is often performed using biopsy‐calibrated two‐dimensional breath‐hold Cartesian gradient echo (2D BH GRE) R2*‐MRI. However, breath‐holding is not possible in most pediatric patients or those with respiratory problems, and three‐dimensional free‐breathing radial GRE (3D FB rGRE) has emerged as a viable alternative.

Keywords: biopsy calibrated; gradient echo; hepatic iron; breathing radial; iron; free breathing

Journal Title: Journal of Magnetic Resonance Imaging
Year Published: 2021

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