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Prospective Evaluation of Virtual MR Elastography With Diffusion‐Weighted Imaging in Subjects With Nonalcoholic Fatty Liver Disease

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Non‐alcoholic fatty liver disease (NAFLD) is increasingly common worldwide and can lead to the development of cirrhosis, liver failure and cancer. Virtual magnetic resonance elastography (VMRE), which is based on… Click to show full abstract

Non‐alcoholic fatty liver disease (NAFLD) is increasingly common worldwide and can lead to the development of cirrhosis, liver failure and cancer. Virtual magnetic resonance elastography (VMRE), which is based on a shifted apparent diffusion coefficient (sADC), is a potential noninvasive method to assess liver fibrosis without the specialized hardware and expertise required to implement traditional MR elastography (MRE). Although hepatic steatosis is known to confound ADC measurements, previous studies using VMRE have not corrected for hepatic fat fraction.

Keywords: elastography; diffusion; fatty liver; liver disease; prospective evaluation

Journal Title: Journal of Magnetic Resonance Imaging
Year Published: 2022

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