LAUSR

To analyze the relationship between the factors related to the occurrence of HBV‐GN and serum HBsAg‐positive glomerulonephritis. A total of 56 patients were enrolled in the present study. All enrolled cases were divided into two groups according to whether HBsAg and/or HBcAg was present in renal kidney tissue: patients with Hepatitis B virus‐associated nephritis (HBV‐GN group, 30 cases) and patients with hepatitis B virus‐combined nephritis (HBV‐CG group, 26 cases). We sought to analyze the differences in clinical features and pathological characteristics in both groups. The rate of HBeAg positivity in the HBV‐GN group was considerably increased in the HBV‐CG group (P < 0.05), and the number of patients with HBsAg+HBeAg+HBcAb+ in the HBV‐GN group was considerably increased in the HBV‐CG group (21 cases vs 10 cases) (P < 0.05). Moreover, the number of MCD patients diagnosed by renal biopsy in the HBV‐GN group was reduced compared with the HBV‐CG group (1 case vs 7 cases) (P < 0.05). HBV infection and high‐virus proliferation status were closely related with HBV‐GN.