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Clinical Outcomes in COVID‐19 Patients Treated with Tocilizumab: An Individual Patient Data Systematic Review

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Current evidence suggests an important role of the interleukin‐6 (IL‐6) pathway in severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐related cytokine release storm in severely ill coronavirus disease 2019 (COVID‐19) patients.… Click to show full abstract

Current evidence suggests an important role of the interleukin‐6 (IL‐6) pathway in severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐related cytokine release storm in severely ill coronavirus disease 2019 (COVID‐19) patients. Inhibition of the IL‐6 pathway with tocilizumab has been employed successfully in some of these patients but the data is mostly consistent of case reports and series.

Keywords: covid patients; patients treated; clinical outcomes; outcomes covid; tocilizumab individual; treated tocilizumab

Journal Title: Journal of Medical Virology
Year Published: 2020

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