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A more detailed understanding of Treg cells in COVID‐19 infection will broaden our knowledge of the COVID‐19 immunopathology and give us more insight into the curative immune‐based strategies. We systematically… Click to show full abstract
A more detailed understanding of Treg cells in COVID‐19 infection will broaden our knowledge of the COVID‐19 immunopathology and give us more insight into the curative immune‐based strategies. We systematically searched electronic databases (PubMed, Google Scholar, EMBASE) and identified 18 eligible studies. Despite the inconsistencies between the results, we observed a trend toward decreasing Treg levels in severe COVID‐19 patients. This finding underlines the hypothesis that Tregs play a role in the pathogenesis of COVID‐19. Further studies on Tregs' functional aspects are necessary to illustrate Tregs' potential role in COVID‐19 disease.
Journal Title: Journal of Medical Virology
Year Published: 2021
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