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A third booster dose may be necessary to mitigate neutralizing antibody fading after inoculation with two doses of an inactivated SARS-CoV-2 vaccine.

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Neutralizing antibodies in volunteers who received two doses of an inactivated SARS-CoV-2 vaccine deceased over several months. A three-dose procedure study suggested that the boost conferred by a third dose… Click to show full abstract

Neutralizing antibodies in volunteers who received two doses of an inactivated SARS-CoV-2 vaccine deceased over several months. A three-dose procedure study suggested that the boost conferred by a third dose rescued the waning of neutralizing antibodies after the two doses of the inactivated vaccine. Importantly, a booster dose can also elicit a more robust neutralizing antibody response than the two-dose procedure. This article is protected by copyright. All rights reserved.

Keywords: cov vaccine; sars cov; doses inactivated; booster dose; inactivated sars; two doses

Journal Title: Journal of medical virology
Year Published: 2021

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