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The Coronavirus disease (COVID-19), caused by sever acute respiratory syndrome coronavirus -2 (SARS-CoV-2) and its various emerging variants, is posing very high health threats with its continued pandemic waves with 5.5 millions deaths out of 272 million confirmed cases reported worldwide as of December 17, 2021, and recently again a rapid surge of cases is being seen at global level. 1-41-4 After the Alpha, Beta, Gamma and Delta SARS-CoV-2 variant of concerns (VOCs), the most recent B.1.1.529 variant (named as Omicron) classified as VOC by WHO on 26 November 2021, is creating alarming situations worldwide. The first case of Omicron was documented from Botswana, South Africa in early November month, and within a very short time this variant has now spread rapidly to 108 countries with nearly 1.5 lakh reported cases and 26 deaths as on December 25, 2021. 5-95-9 This article is protected by copyright. All rights reserved.