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Brain abnormalities in cognition, anxiety, and depression regulatory regions in adolescents with single ventricle heart disease

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Single ventricle heart disease (SVHD) adolescents show cognitive impairments and anxiety and depressive symptoms, indicating the possibility of brain injury in regions that control these functions. However, brain tissue integrity… Click to show full abstract

Single ventricle heart disease (SVHD) adolescents show cognitive impairments and anxiety and depressive symptoms, indicating the possibility of brain injury in regions that control these functions. However, brain tissue integrity in cognition, anxiety, and depression regulatory sites in SVHD remains unclear. We examined brain tissue changes in SVHD compared to controls using T2‐relaxometry procedures, which measure free water content and show tissue injury.

Keywords: anxiety; heart disease; single ventricle; cognition anxiety; ventricle heart; brain

Journal Title: Journal of Neuroscience Research
Year Published: 2018

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