LAUSR

the biomedical It the medical research that is concerned with facilitating the practical application of scientific discoveries to the development and implementation of new ways to prevent, diagnose, translational research can also be seen as transfer research within a continuum that includes basic biological research at one end and innovative practical clinical research at the other. Within this continuum of knowledge transfer, translational research represents the first stage of scientific and technical developments that truly takes into account the complex phenotype of the patients and their pathology for creating new in vivo and in silico models, discovering new cellular or molecular mechanisms and transfer to medical applications. This translational research needs to be de-veloped close to the patient, in order to allow a bidirectional flow of knowledge from basic research to clinical implementation and from clinical observations to preclinical and/or basic research. Thus, while translational research information flow typically is from the labora-tory to the hospital, clinical and histopathological observations in also fostered the development of new