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Rationale and design of the HINODE study: Heart failure indication and sudden cardiac death prevention trial Japan

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Randomized trials in Western countries have provided evidence that prophylactic implantable cardioverter‐defibrillator (ICD) therapy reduces mortality in heart failure (HF) patients with reduced left ventricular ejection fraction. However, the risk… Click to show full abstract

Randomized trials in Western countries have provided evidence that prophylactic implantable cardioverter‐defibrillator (ICD) therapy reduces mortality in heart failure (HF) patients with reduced left ventricular ejection fraction. However, the risk of life‐threatening ventricular arrhythmias in Japanese HF patients sharing similar risk factors is still unknown.

Keywords: heart; heart failure; rationale design; hinode study; design hinode

Journal Title: Journal of Arrhythmia
Year Published: 2021

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