LAUSR

BACKGROUND The triclosan-containing dentifrices are effective in controlling biofilm formation and maintaining gingival health, however there is limited information on their effects during the periodontal maintenance phase. Therefore, the aim of this study was to evaluate the clinical effects of a toothpaste containing 0.3% triclosan on the periodontal parameters of subjects that have been treated for peri-implantitis and were enrolled in a regular maintenance program. METHODS Subjects presenting at least one implant with peri-implantitis and received surgical anti-infective therapy were selected. Sixty days post-surgery (baseline), subjects were randomized into two groups: (i)toothpaste containing 0.3% triclosan+2.0% PVM/MA copolymer (Gantrez™)+1450 ppm fluoride (test) or (ii)toothpaste containing 1450 ppm fluoride (control), and were instructed to brush with the assigned toothpaste twice/day for 2 years. They received clinical monitoring at baseline, 3, 6, 12, 18 and 24 months, and professional maintenance every 3 months. RESULTS Eighty-eight subjects with natural teeth were enrolled in the study (Test, n: 39; Control, n:49). The test group showed a greater reduction in the percentage of sites exhibiting bleeding on probing (primary outcome) and lower levels of plaque in comparison with the control group after 24 months (p<0.05). The mean percentage of sites with probing depth ≥ 5mm was reduced over the course of the study only in the test group (p<0.05). CONCLUSION A toothpaste containing 0.3% triclosan was more effective than a regular fluoride toothpaste in improving the periodontal clinical condition around natural teeth of periodontally healthy subjects enrolled in a regular maintenance program for 2 years. This article is protected by copyright. All rights reserved.