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BACKGROUND to examine the association of periodontitis with telomere length (TL) and effect modification by population characteristics. METHODS We analyzed data from 3,478 participants from the 1999 to 2002 National… Click to show full abstract
BACKGROUND
to examine the association of periodontitis with telomere length (TL) and effect modification by population characteristics.
METHODS
We analyzed data from 3,478 participants from the 1999 to 2002 National Health and Nutrition Examination Survey. Pocket depth, attachment loss, and bleed on probing (BOP, available for 1,973 participants only) were examined on the distal, mesial, or mid-facial site of each tooth in two randomly selected quadrants. We defined periodontitis severity according to the CDC/AAP guideline. TL from leukocytes was measured with qPCR. We used linear and logistic regression to examine the adjusted association of different severity of periodontitis and BOP with continuous TL (bp) and dichotomized short TL (
Journal Title: Journal of periodontology
Year Published: 2020
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