LAUSR

BACKGROUND This study aimed to evaluate the effect of scaling and root planing (SRP) on levels of plasma C-reactive protein (CRP). METHODS A total of 30 patients with advanced periodontitis as determined by Clinical Periodontal Sum Score (CPSS) were recruited. Venous whole blood samples were drawn from to obtain serum samples were obtained from all participants at baseline and 1 month after SRP (post-SRP). High-sensitivity CRP (hs-CRP) was measured by highly sensitive immunoturbidimetric assay. Wilcoxon signed-rank test was used for data analysis. Spearman's rank correlation analysis was conducted to test the correlations between CPSS and hs-CRP at baseline and post-SRP. RESULTS There was a statistically significant reduction in the post-SRP CPSS values from the baseline values (z = 4.783, p < 0.0001). Similarly, there was a statistically significant reduction in the post-SRP hs-CRP levels from the baseline levels (z = 4.782, p < 0.0001). Moreover, there was positive association between the baseline levels of CPSS and hs-CRP (ρ = 0.5703) and the post-SRP values of CPSS and hs-CRP (ρ = 0.7507). CONCLUSION The present study suggests that SRP can significantly reduce the levels of CRP. This article is protected by copyright. All rights reserved.