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A randomized controlled trial evaluating the effect of epithelial removal on free soft tissue autograft healing.

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BACKGROUND The purpose of this study is to determine if there is a difference in dimensional change of a free soft tissue autograft (FSTA) with epithelium compared to without epithelium.… Click to show full abstract

BACKGROUND The purpose of this study is to determine if there is a difference in dimensional change of a free soft tissue autograft (FSTA) with epithelium compared to without epithelium. The secondary aim is to determine the patient and professional evaluation of color match and graft texture between the two groups. METHODS Patients with ≤2mm keratinized tissue indicated for a FSTA were randomly assigned to control group: FSTA with epithelium or test group: de-epithelialized FSTA. The vertical and horizontal measurements of the grafts were taken at surgery, and 1-, 3-, and 6-months post-operatively. Patients were asked to evaluate the color match at each post-operative timepoint on a Numeric Rating Scale-21 (NRS-21). Professional assessment of color match and graft texture were evaluated on images at the same timepoints. RESULTS Forty-six patients and 55 grafts were included in the study. For change in graft height, width, and area, there were no significant differences between the treatment groups at any timepoint. Graft height and area in both groups decreased significantly from baseline to month 1 (p<.001), but no other difference was significant over time. When patients and professionals used the NRS-21 scale for evaluation of color match between the graft site and the surrounding soft tissue, there was no significant difference between the treatment groups. Similarly, evaluation of texture match on color images and black-and-white images revealed no significant differences between or within groups. CONCLUSION De-epithelialized FSTA showed no difference in dimensional change or color and texture match compared to FSTA with epithelium. This article is protected by copyright. All rights reserved.

Keywords: free soft; color; soft tissue; match; graft; tissue

Journal Title: Journal of periodontology
Year Published: 2023

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