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A yak bone collagen‐derived antioxidant peptide with excellent stability alleviates UVA‐induced photoaging by activating the Keap1/Nrf2 signaling pathway

Prolonged exposure to ultraviolet A (UVA) rays can trigger oxidative stress, leading to skin photoaging. Our team previously identified four antioxidant peptides derived from yak bone collagen through bioinformatics prediction.… Click to show full abstract

Prolonged exposure to ultraviolet A (UVA) rays can trigger oxidative stress, leading to skin photoaging. Our team previously identified four antioxidant peptides derived from yak bone collagen through bioinformatics prediction. The objective of this study was to screen out one most promising application antioxidant peptide through molecular docking, in vitro antioxidant activity verification and stability assessment, and elucidate its mechanism of action.

Keywords: stability; yak bone; antioxidant peptide; bone collagen

Journal Title: Journal of the Science of Food and Agriculture
Year Published: 2025

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