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Ratio‐based staging systems are better than the 7th and 8th editions of the TNM in stratifying the prognosis of gastric cancer patients: A multicenter retrospective study

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The current and the previous editions of the tumor‐node‐metastasis (TNM) system for gastric cancer (GC; TNM8 and TNM7) have a high risk of stage‐migration bias when the node count after… Click to show full abstract

The current and the previous editions of the tumor‐node‐metastasis (TNM) system for gastric cancer (GC; TNM8 and TNM7) have a high risk of stage‐migration bias when the node count after gastrectomy is suboptimal. Hence, they are possibly not the optimal staging systems for GC patients. This study aims to compare the TNM with two systems less affected by the stage‐migration bias, namely, the lymph nodes ratio (LNR) and the log odds of positive lymph nodes (LODDS), to assess which one is the best in stratifying the prognosis of GC patients.

Keywords: gastric cancer; ratio based; stratifying prognosis; staging systems

Journal Title: Journal of Surgical Oncology
Year Published: 2019

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