Deep learning utilizing convolutional neural networks (CNNs) applied to hematoxylin & eosin (H&E)‐stained slides numerically encodes histomorphological tumor features. Tumor heterogeneity is an emerging biomarker in colon cancer that is,… Click to show full abstract
Deep learning utilizing convolutional neural networks (CNNs) applied to hematoxylin & eosin (H&E)‐stained slides numerically encodes histomorphological tumor features. Tumor heterogeneity is an emerging biomarker in colon cancer that is, captured by these features, whereas microsatellite instability (MSI) is an established biomarker traditionally assessed by immunohistochemistry or polymerase chain reaction.
               
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