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Prognostic roles of leptin‐signaling proteins, PD‐L1, and tumor‐infiltrating lymphocytes in surgically‐resected biliary tract cancers

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Biliary tract cancers are rare, with a poor patient prognosis. Leptin and programmed death‐ligand 1 (PD‐L1) influence CD8+ and forkhead box P3 (FOXP3)+ lymphocytes, and thus, cancer cell growth. We… Click to show full abstract

Biliary tract cancers are rare, with a poor patient prognosis. Leptin and programmed death‐ligand 1 (PD‐L1) influence CD8+ and forkhead box P3 (FOXP3)+ lymphocytes, and thus, cancer cell growth. We aimed to define the prognostic implications of these variables and the clinicopathological features of biliary tract cancers.

Keywords: roles leptin; prognostic roles; leptin signaling; tract cancers; biliary tract

Journal Title: Journal of Surgical Oncology
Year Published: 2022

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