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Preoperative radiotherapy has improved outcomes in rectal cancer patients, however, the optimal interval between radiation and proctectomy is unknown. A review of contemporary literature suggests an 8–12 week interval between… Click to show full abstract
Preoperative radiotherapy has improved outcomes in rectal cancer patients, however, the optimal interval between radiation and proctectomy is unknown. A review of contemporary literature suggests an 8–12 week interval between radiation and surgery likely improves tumor response rates for rectal cancer patients undergoing proctectomy, which may convey modest improvements in long‐term oncologic outcomes. Prolonged radiation‐surgery intervals may expose surgeons to pelvic fibrosis, however, which may impact later‐term proctectomies and compromise perioperative and oncologic outcomes.
Journal Title: Journal of Surgical Oncology
Year Published: 2023
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