LAUSR

A simple and efficient multiresidue method using dispersive solid phase extraction and LC-MS/MS was developed for the targeted analysis of indaziflam and its five metabolites (indaziflam-diaminotriazine, indaziflam-carboxylic acid, indaziflam-triazine indanone, indaziflam-hydroxyethyl, indaziflam-olefin) in pitaya samples (including roots, plants, flowers, peels, pulp and whole fruit). The analytes were extracted with acetonitrile, and the extracts were purified using multiwalled carbon nanotubes. The method was validated using pitaya samples spiked at 0.5, 5 and 50 μg kg-1 , and the average recoveries varied from 61.1% to 103.7% with relative standard deviations lower than 12.7% (n = 5). This method exhibited sufficient linearity within the concentration range of 0.1-100 μg L-1 . The limits of detection and quantification were in the ranges of 0.001-0.1 μg kg-1 and 0.003-0.3 μg kg-1 , respectively. The method was successfully applied to analyze pitaya samples in Nanning, and no indaziflam or its metabolites were detected in the samples analyzed. This article is protected by copyright. All rights reserved.