LAUSR

Aristolochic acid I is a toxic compound found in the genus of Aristolochia plants, which are commonly used as herbal cough treatment medicines. To remove the aristolochic acid I in extract efficiently and selectively, a molecular imprinted polymer composited ethylimidazole ionic liquid-based zeolitic imidazolate framework-67 was synthesized and used as the adsorbent. Under the condition optimized by the software Design Expert, the sorbent showed highest adsorption amount of 34.25 mg/g in methanol/water (95.00:5.00, v/v) at 39 °C for 138.00 min. The sorbent was then applied to solid phase extraction to isolate aristolochic acid I from the extract of the herbal plant Fibraurea Recisa Pierre. 0.043 mg/g of aristolochic acid I was obtained after the loading, washing, and elution processes. The limit of detection of 2.41 × 10-5 mg/mL and good recoveries of provided evidence for the accuracy of this method. This article is protected by copyright. All rights reserved.