LAUSR

Halitosis with the main components of trace volatile sulfur compounds widely affects the quality of life. In this study, an adaptable active sampling system with two sample-collection modes of direct injection and solid phase microextraction was developed for the rapid and precise determination of trace volatile sulfur compounds in human halitosis coupling with GC-flame photometric detection. The active sampling system was well designed and produced for efficiently sampling and precisely determining trace volatile targets in halitosis under the optimized sampling and detection conditions. The analytical method established was successfully applied for the determination of trace targets in halitosis. The LODs of H2 S, CH3 SH, CH3 SCH3 by direct injection were in range of 0.0140-23.0 μg/L with good recoveries ranging in 82.2-118% and satisfied RSDs of 0.4-9.5% (n = 3) respectively. The LODs of CH3 SH and CH3 SCH3 by solid phase microextraction were 2.03 and 0.186 × 10-3 μg/L with good recoveries ranging in 98.3-108% and RSDs of 5.9-9.0% (n = 3). Trace volatile targets in positive real samples could be actually found and quantified by combination of direct injection and solid phase microextraction. This method was reliable and efficient for the determination of trace volatile sulfur compounds in halitosis. This article is protected by copyright. All rights reserved.