LAUSR

In this study, sample pretreatment methods have been developed for the determination of chlorpyrifos, diazinon and their byproducts contained in cherry tomato and perilla leaf using LC-MS/MS. To optimize a quick, easy, cheap, effective, rugged and safe method, the recoveries at each step were evaluated. The steps improved the recoveries of chlorpyrifos, chlorpyrifos oxon, diazinon, diazoxon, and 2-isopropyl-6-methyl-4-pyrimidinol up to 80% or more by removing interferents, but diethyl phosphate was almost lost during the partition procedure, and the 3,5,6-trichloro-2-pyridinol recovery was below 65%. Therefore, the compounds were evaluated using different solvent compositions based on a quick polar pesticides method; 100% methanol showed acceptable extraction results. The optimized method provided method detection limits ranging from 0.03 to 1.22 ng/g and good linearities (R2 >0.996). The recovery values were between 82.1 and 113.3%. The intra- and inter-day reproducibility was evaluated to be within 8.6% and 9.9%, respectively. The method was applied to determine the degradation efficiency of chlorpyrifos and diazinon and their byproducts formed during plasma treatment. This article is protected by copyright. All rights reserved.