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Collagen Matrix Combined With Hydroxyapatite and Nasoseptal Flap for Skull Base Reconstruction

Extended endoscopic endonasal transsphenoidal approaches (ExEETSA) commonly result in high‐flow cerebrospinal fluid (CSF) leaks that demand robust reconstruction strategies. Although nasoseptal flap (NSF) is a standard reconstructive technique, high‐flow grade… Click to show full abstract

Extended endoscopic endonasal transsphenoidal approaches (ExEETSA) commonly result in high‐flow cerebrospinal fluid (CSF) leaks that demand robust reconstruction strategies. Although nasoseptal flap (NSF) is a standard reconstructive technique, high‐flow grade 3 CSF leaks require additional rigid reconstruction. This study evaluated the long‐term outcomes of collagen matrix‐hydroxyapatite (HXA)‐NSF for rigid skull base reconstruction without lumbar drain.

Keywords: base reconstruction; skull base; reconstruction; collagen matrix; nasoseptal flap

Journal Title: Laryngoscope Investigative Otolaryngology
Year Published: 2025

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