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Nano‐Pulse Stimulation Induces Changes in the Intracellular Organelles in Rat Liver Tumors Treated In Situ

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Nano‐pulse stimulation (NPS) therapy is the application of ultrafast pulses of high amplitude electrical energy to tissues to influence cell function. Unique characteristics of these pulses enable electric field penetration… Click to show full abstract

Nano‐pulse stimulation (NPS) therapy is the application of ultrafast pulses of high amplitude electrical energy to tissues to influence cell function. Unique characteristics of these pulses enable electric field penetration into the interior of cells and organelles to generate transient nanopores in both organelle and plasma membranes. The purpose of this study is to document the temporal and physical changes in intracellular organelles following NPS therapy using electron microscopy.

Keywords: changes intracellular; nano pulse; pulse stimulation; intracellular organelles

Journal Title: Lasers in Surgery and Medicine
Year Published: 2020

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