Combined sequential treatments with multiple modalities such as lasers and soft‐tissue fillers are commonly required for the treatment of atrophic acne scars. Recently, fractional treatment with picosecond‐domain lasers has proven… Click to show full abstract
Combined sequential treatments with multiple modalities such as lasers and soft‐tissue fillers are commonly required for the treatment of atrophic acne scars. Recently, fractional treatment with picosecond‐domain lasers has proven to be effective for skin rejuvenation and scar treatment. However, little is known about the effects of picosecond‐domain fractional laser treatment over hyaluronic acid fillers (HAFs). We aimed to evaluate the in vivo tissue responses to 1064 nm picosecond‐domain fractional neodymium:yttrium‐aluminum‐garnet (Nd:YAG) laser treatments using microlens array (MLA) applied over pre‐injected HAF in rats. In addition, we evaluated the efficacy and safety of this combined same‐day treatment for atrophic acne scars in patients.
               
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